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MYP_127230
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Basic Information
L-K6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C75H145N19O15
Standard
Sequence
IKKILSKIKKLLK
Physicochemical Analysis
1553.07 Da
10.70
5.75
5.54
0.4426
0.05
0.80
-0.14
-15.14
180.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
588.87
-0.74
21.0
21.0
62.0
109.0
0.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008073 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B. cereus
6.25 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0008761 VERIFIED: YES
Provenance & Taxonomy
some cationic antimicrobial peptides [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Rabbit red blood cells: modest hemolytic activity(as show in Fig.2)
PaperPubMed PMID: 28811617 PMID28811617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28811617/
RECORD: Rec_0021877 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P.mirabilis
>100 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0052992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae
>100 μM
MIC
PaperInvestigation of the role of tryptophan residues in cationic antimicrobial peptides to determine the mechanism of antimicrobial action.
RECORD: Rec_0059092 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antibacterial
Streptococcus mutans CGMCC 1.2500
3.3, 6.25 μM
Crystal violet assay
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