Peptide Database

Peptide NamePeptidoglycan hydrolase

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length584 amino acids

Chemical FormulaC2864H4543N789O937S5

DescriptionStandard

        MKKIVPLLTGAFVIASSTTTFLSTPVNAKNLDEKENEIKETNESDKQEIPLLDSHDKEEPDEQEEIEVEKNVESEELAEKDSDSSTEIAETTDATDEQTASTEESKEGATPTDSKEDTTPTSENVEAEKEIVTVDAANSNPTSSSVGKNQSDKINTSSSQKKTTTAPKKKNKTAKTKVHKSTPFAPGKSQSSKRTTTNGDTTSSVTMGENSYTFSPNFTTQRFIKTIGEDARNLGQKHGLYASVMIAQAILESASGNSSLASPPNYNLFGIKGSYKGTSVNFATQEDDGSGNHYTIRANFRKYPSYKQSLEDYVQLIRGGLPYNHNFYSGVWKSNTKSYQDATRFLMGRYATDTSYAAKLNGLIRTYNLTAYDIPAVKVENLTNPILDKKTENSKNNERDIVKNITVATEKSVQPNRKVNKKQATVAHTVKAGESLVSICRLYQVPLHQIVSQNGLNSYLLAVGQVLEVGKTIRLKEEEKLSYSVKYFERDLEHFSKPAGNELFLRLNTPFFKNYSVKAYRQRPAGFYSVQRGDTLAKIAKRFKISVQSLRRWNNLEGYLIYEGQQLRLTPWLDEFLPQVFTTI
    

Molecular Weight65180.76 Da

Isoelectric Point (pI)8.12

Net Charge (pH 7.0)2.27

Net Charge (pH 7.4) 1.42

Charge Density (pH 7.0) 0.0039

GRAVY Index-0.75

Hydrophobic Moment 0.83

Boman Index-0.12

Instability Index37.90

Aliphatic Index 69.47

Aromaticity 0.0805

Extinction Coeff. Reduced 52260.00

Extinction Coeff. Oxidized 52260.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037491 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus dispar ATCC 51266 [Bacterium]

FamilyGlycosyl hydrolase 73

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Non-hemolytic Non-ribosomal

MethodQualitative functional evidence