Peptide Database

Peptide NameEnterocin E-760 (Bacteriocin E-760)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC269H403N81O80S4

DescriptionStandard

        NRWYCNSAAGGVGGAAVCGLAGYVGEAKENIAGEVRKGWGMAGGFTHNKACKSFPGSGWASG
    

Molecular Weight6179.83 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)2.82

Net Charge (pH 7.4) 2.51

Charge Density (pH 7.0) 0.0455

GRAVY Index-0.18

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index42.56

Aliphatic Index 47.42

Aromaticity 0.1129

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2559.43

LogP -32.59

H-bond Donors 93.0

H-bond Acceptors 88.0

Rotatable Bonds 198.0

Heavy Atoms 434.0

Ring Count 12.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426982 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus sp. [Bacterium]

FamilyEnterocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetCampylobacter C/D

Activity0.2 μg/mL

MethodMIC

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