Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC730H1138N212O204S5

DescriptionStandard

        MPKVQFKQRPATDYIVIHCAATKVSMDIGVREINQWHVQQGWLGIGYHFVIRRNGTVENGRPHDVIGSHVKNYNSRALGICLAGGIDDNGKPQNNFTPEQFASLKLLLVAYKRQYPQAQIVGHHDLDSGKACPSFKVSEWLKTAGI
    

Molecular Weight16308.47 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.08

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0417

GRAVY Index-0.36

Hydrophobic Moment 0.59

Boman Index0.02

Instability Index32.51

Aliphatic Index 84.11

Aromaticity 0.0890

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6692.75

LogP -65.32

H-bond Donors 230.0

H-bond Acceptors 222.0

Rotatable Bonds 537.0

Heavy Atoms 1151.0

Ring Count 30.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011204 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas phage Pf1 ERZ-2017 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic