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MYP_127203
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Basic Information
RN4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
47 amino acids
C253H389N81O71S4
Standard
Sequence
QDGMYQRFLRQHVHPEETGGSDRYSNLMMQRRKMTLYHSKRFNTFIH
Physicochemical Analysis
5829.56 Da
10.15
4.11
3.69
0.0875
-1.23
0.62
-0.31
64.05
39.36
0.1277
4470.00
4470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2521.10
-26.16
90.0
83.0
197.0
409.0
11.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0099828 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
RECORD: Rec_0151336 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
RECORD: Rec_0249843 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
RECORD: Rec_0384712 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028 (MFC100 = 4.00 ± 0.50 microM (Sabouraud Broth)), C. albicans ATCC 90028 (MFC100 = 3.75 ± 0.20 microM (PBS)), (IC50 = 1.80 ± 0.30 microM)
1.80 ± 0.30 μM
IC50
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/
RECORD: Rec_0389970 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID31540052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31540052/