Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length494 amino acids

Chemical FormulaC2415H3853N621O712S20

DescriptionStandard

        MLSSAILLLFLLPCACGENPAIQLILTNKGLQYGKHAGAGWVQDKLGSVTLPDLSGDFSLLIGSVHYTLSGISIEKCDFPEPSVEFFQNSTGLKASLSGLSVALTGEWTSSYGIIHDEGTFSMAVFNVDVLSVVELGRDADGRLSLSSLLCEAHVQDVQIQIRGGASWIIQLIVDHNRGRIRGDIESRICPQMEEAIVELERHLQAVNVSFDVGEALSLDLPLSLPPVVSASALSLGLKGEFYSIKTHKEPPFEAQPFTLPPQPGYMLSVGLSEFTLNSAFYGFFSSGLLQLLVDDGMLAQMFPDLLMNLQVYAREAPMFSLQPDAGKLSVEGTVKAFAIFPNGTQIPVFTLDSESLFSSKMRVADGRVKGSVTMDNLTLSLVASEVGPFSTDSLEKMVRMGVKMVVLPKINQILASGILLPRTKYGQLVNSVLTMEEVSMSEDVILLKTKPTLFELTSGSFLSGIHRLLFRRSAVSNRLTRALAIAVRTKTYF
    

Molecular Weight53620.46 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-10.78

Net Charge (pH 7.4) -11.58

Charge Density (pH 7.0) -0.0218

GRAVY Index0.26

Hydrophobic Moment 0.72

Boman Index0.17

Instability Index37.08

Aliphatic Index 106.34

Aromaticity 0.0769

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316612 VERIFIED: NO

Provenance & Taxonomy

OrganismSalarias fasciatus (Jewelled blenny) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria