Peptide Database

Peptide NameObestatin

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC116H170N32O32

DescriptionStandard

        FNAPFDVGIKLSGPQYHQHGQAL
    

Molecular Weight2524.79 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0029

GRAVY Index-0.38

Hydrophobic Moment 0.41

Boman Index0.15

Instability Index22.87

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1019.44

LogP -9.56

H-bond Donors 32.0

H-bond Acceptors 34.0

Rotatable Bonds 78.0

Heavy Atoms 180.0

Ring Count 7.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080873 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyObestatin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Growth regulation Development regulation Receptor modulation Sleep regulation Wake regulation

Targetis the ligand for growth hormone secretagogue receptor

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0148420 VERIFIED: NO