Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length263 amino acids

Chemical FormulaC1359H2127N347O383S7

DescriptionStandard

        MEKPILKKLNEMLCPIITGEVEALNANLSMLEVLRKIDNYTLLDYSLISSPEITENYFDLNLKGVFYPLKSLRYPPFPSVPFVLPERRDSMLYIGISEYFFKSASYAYFTAGAFSFTLTTKEISNHLLHNSQAHGNMLSRVASTNVALAILGQRLICSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISLVNSDIEVLEGFLLISTDLKYKTSKQQPGFHGWEDLHLISGQWSGKPTP
    

Molecular Weight29678.98 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)1.12

Net Charge (pH 7.4) 0.45

Charge Density (pH 7.0) 0.0043

GRAVY Index-0.01

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index47.52

Aliphatic Index 104.18

Aromaticity 0.1027

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113307 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyBPI

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence