Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 4.6

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC168H282N50O45S7

DescriptionStandard

        VFINAKCRGSPECLPKCKQAIGKAAGKCMNGKCKCYP
    

Molecular Weight3946.80 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)6.67

Net Charge (pH 7.4) 6.36

Charge Density (pH 7.0) 0.1803

GRAVY Index-0.28

Hydrophobic Moment 0.52

Boman Index-0.08

Instability Index53.88

Aliphatic Index 50.27

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1535.62

LogP -16.67

H-bond Donors 57.0

H-bond Acceptors 59.0

Rotatable Bonds 133.0

Heavy Atoms 270.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086816 VERIFIED: NO

Provenance & Taxonomy

OrganismTityus stigmurus [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-28, 13-33, 17-35

Bio-Activity Profile

Function

Toxin

TargetKv1.2/KCNA2, Kv1.3/KCNA3