Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC153H240N44O46S2

DescriptionStandard

        KCNTVTCATQRLANFLIHSSNNFGAIFSPPSVG
    

Molecular Weight3495.94 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0553

GRAVY Index0.16

Hydrophobic Moment 0.48

Boman Index0.15

Instability Index22.58

Aliphatic Index 73.94

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1450.60

LogP -19.43

H-bond Donors 51.0

H-bond Acceptors 51.0

Rotatable Bonds 109.0

Heavy Atoms 245.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282216 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)