Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC302H465N75O110S5

DescriptionStandard

        MSNTQLLEVLGTETFDVQEDLFAFDTTDTTIVASNDDPDTRFSSLSLCSLGCTGVKNPSFNSYCC
    

Molecular Weight7066.68 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-8.53

Net Charge (pH 7.4) -8.81

Charge Density (pH 7.0) -0.1312

GRAVY Index-0.08

Hydrophobic Moment 0.38

Boman Index0.07

Instability Index26.76

Aliphatic Index 68.92

Aromaticity 0.0923

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2991.74

LogP -39.29

H-bond Donors 106.0

H-bond Acceptors 107.0

Rotatable Bonds 228.0

Heavy Atoms 492.0

Ring Count 8.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0184298 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence