Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length116 amino acids

Chemical FormulaC603H912N168O175S

DescriptionStandard

        MSVSNNGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSKDSVLLAQFIKSNQNNVSQGYSPYVPEEGYYYGPNEIVKKFQIHHVVAIEHGGGVYDIDNFRIVTPRLHDEIHYRR
    

Molecular Weight13346.78 Da

Isoelectric Point (pI)6.28

Net Charge (pH 7.0)-1.96

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0169

GRAVY Index-0.55

Hydrophobic Moment 0.52

Boman Index-0.03

Instability Index43.51

Aliphatic Index 80.60

Aromaticity 0.1207

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 15930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5534.63

LogP -50.37

H-bond Donors 188.0

H-bond Acceptors 180.0

Rotatable Bonds 436.0

Heavy Atoms 947.0

Ring Count 27.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216525 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Nuclease Endonuclease Non-hemolytic Non-ribosomal