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MYP_126981
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Basic Information
Defensin-B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
43 amino acids
C186H303N59O55S6
Standard
Sequence
VTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN
Physicochemical Analysis
4438.15 Da
8.34
1.85
1.45
0.0430
0.47
0.43
0.15
17.81
86.28
0.0465
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1826.37
-22.73
69.0
65.0
146.0
306.0
4.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0246804 VERIFIED: NO
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-34; 20-39; 24-41
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0255411 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-34, 20-39, 24-41
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
1.2-2.5 μM
MIC
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0313397 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-34, 20-39, 24-41
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus megaterium
1.2-2.5 μM
MIC
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0348478 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B.megaterium
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0422892 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
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