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MYP_126981
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Basic Information
Defensin-B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
43 amino acids
C186H303N59O55S6
Standard
Sequence
VTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN
Physicochemical Analysis
4438.15 Da
8.34
1.85
1.45
0.0430
0.47
0.43
0.15
17.81
86.28
0.0465
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1826.37
-22.73
69.0
65.0
146.0
306.0
4.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0128411 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0144481 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-34, 20-39, 24-41
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0154869 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Xenorhabdus japonicus
40 μM
MIC
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0184154 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-34, 20-39, 24-41
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
japonicus
20-40 μM
MIC
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0234219 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-34, 20-39, 24-41
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
2.5-5 μM
MIC
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
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