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MYP_126981
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Basic Information
Defensin-B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
43 amino acids
C186H303N59O55S6
Standard
Sequence
VTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN
Physicochemical Analysis
4438.15 Da
8.34
1.85
1.45
0.0430
0.47
0.43
0.15
17.81
86.28
0.0465
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1826.37
-22.73
69.0
65.0
146.0
306.0
4.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037065 VERIFIED: NO
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal
Bacillus megaterium, Bacillus subtilis, Escherichia coli, Micrococcus luteus, Pseudomonas aeruginosa
Qualitative functional evidence
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/; https://www.uniprot.org/uniprotkb/P83668/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0078994 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0079072 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperInsect Biochem Mol Biol. 2001 Dec;32(1):75-84. | http://www.ncbi.nlm.nih.gov/pubmed/11719071 PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0093299 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-34, 20-39, 24-41
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
20-40 μM
MIC
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
RECORD: Rec_0115564 VERIFIED: YES
Provenance & Taxonomy
Anomala cuprea [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
PMID11719071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11719071/
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