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MYP_126966
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Basic Information
Hainanenin 5
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C107H181N29O25S2
Standard
Sequence
FALGAVTKRLPSLFCLITRKC
Physicochemical Analysis
2337.89 Da
10.11
3.74
3.50
0.1780
0.81
0.57
0.15
44.48
116.19
0.0952
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
873.06
-5.96
34.0
31.0
76.0
163.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0047788 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Hainanenin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
22.0 μM
HC50
PaperS. Zhang et al. / Peptides (2012) Hainanenins: a novel family of antimicrobial peptides with strong activity from Hainan cascade-frog Amolops hainanensis, Available online 24 January 2012
RECORD: Rec_0052475 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli 1342
4.7 μg/mL
MIC
PMID22306820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306820/
RECORD: Rec_0061520 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
S. mould 090413
9.4 μg/mL
MIC
PaperHainanenins: A novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis
RECORD: Rec_0072506 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 1349+
18.8 μg/mL
MIC
PMID22306820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306820/
RECORD: Rec_0072523 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Hainanenin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
PaperS. Zhang et al. / Peptides (2012) Hainanenins: a novel family of antimicrobial peptides with strong activity from Hainan cascade-frog Amolops hainanensis, Available online 24 January 2012
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