Peptide Database

Peptide NamehK2p01 derivative KLK2 inhibitor

Function Ontology

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC59H82N16O11

DescriptionStandard

        ARFKVWWAAG
    

Molecular Weight1191.38 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.61

Charge Density (pH 7.0) 0.1795

GRAVY Index0.18

Hydrophobic Moment 0.11

Boman Index0.22

Instability Index-29.55

Aliphatic Index 59.00

Aromaticity 0.3000

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 444.72

LogP -0.81

H-bond Donors 17.0

H-bond Acceptors 13.0

Rotatable Bonds 34.0

Heavy Atoms 86.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0259992 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory

Targetkallikrein related peptidase 2 (Human)

Activity1410 nM

MethodKi