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MYP_126952
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Basic Information
Mitoparan, Mastoparan [A5,8K;A10Aib]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
INLKKLAKLXKKIL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274467 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human astrocytoma U373-MG[50% Cell death = 9.44 microM
PMID22148546;29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0292778 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii
0.42
MIC
PMID22148546;29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0322492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Rat leukemia cells RBL-2H3
15.3 μM
EC50
PMID22148546;29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0325613 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human astrocytoma U373-MG[50% Cell death = 13.95 microM
PMID22148546;29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
RECORD: Rec_0347089 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
16.0
MIC
PMID22148546;29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22148546/
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