Peptide Database

Peptide NameHepcidin antimicrobial peptide 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC452H719N137O138S14

DescriptionStandard

        MKTFSVAVAVAVVLTFICLQESSAVSFTEVQEQEEPMSNDSPVAAHEEMSEESWKMPYNNRHKRSPAGRNKRRRRCRFCCGCCPNMIGCGTCCKF
    

Molecular Weight10729.29 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)2.61

Net Charge (pH 7.4) 2.13

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.40

Hydrophobic Moment 0.35

Boman Index-0.12

Instability Index118.49

Aliphatic Index 48.21

Aromaticity 0.0737

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4454.16

LogP -52.81

H-bond Donors 164.0

H-bond Acceptors 157.0

Rotatable Bonds 355.0

Heavy Atoms 741.0

Ring Count 15.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194845 VERIFIED: NO

Provenance & Taxonomy

OrganismPagrus auriga [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0403904 VERIFIED: YES