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MYP_126891
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Basic Information
Lantibiotic
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
55 amino acids
C241H397N69O81S7
Standard
Sequence
MNNEDFNLDLVTISKENNSGASPRVTSKSLCTPGCKTGILMTCAIKTATCGCHFG
Physicochemical Analysis
5781.60 Da
7.62
0.54
0.19
0.0099
-0.08
0.39
0.05
22.25
65.64
0.0364
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2419.21
-33.49
88.0
90.0
192.0
398.0
5.0
59.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0202404 VERIFIED: NO
Provenance & Taxonomy
Bacilli [other]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7079
RECORD: Rec_0237912 VERIFIED: NO
Provenance & Taxonomy
Streptococcus agalactiae FSL S3-586 [Bacterium]
Lantibiotic
Structure & Mods
thioether-cyclized lantibiotic scaffold [Cyclic]
post-translationally modified ribosomal peptide [Modified]
Lanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A829ICG1/entry
RECORD: Rec_0242392 VERIFIED: YES
Provenance & Taxonomy
Streptococcus agalactiae [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
PaperFirst evidence of production of the lantibiotic nisin P PMID32111904 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32111904/
RECORD: Rec_0254183 VERIFIED: NO
Provenance & Taxonomy
Streptococcus agalactiae ATCC 13813 [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ5795
RECORD: Rec_0371971 VERIFIED: NO
Provenance & Taxonomy
Streptococcus gallolyticus [Bacterium]
Lantibiotic
Structure & Mods
thioether-cyclized lantibiotic scaffold [Cyclic]
post-translationally modified ribosomal peptide [Modified]
Lanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A6C0GY48/entry
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