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MYP_126891
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Basic Information
Lantibiotic
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
55 amino acids
C241H397N69O81S7
Standard
Sequence
MNNEDFNLDLVTISKENNSGASPRVTSKSLCTPGCKTGILMTCAIKTATCGCHFG
Physicochemical Analysis
5781.60 Da
7.62
0.54
0.19
0.0099
-0.08
0.39
0.05
22.25
65.64
0.0364
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2419.21
-33.49
88.0
90.0
192.0
398.0
5.0
59.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036042 VERIFIED: NO
Provenance & Taxonomy
Streptococcus suis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A116QG75/entry
RECORD: Rec_0085811 VERIFIED: NO
Provenance & Taxonomy
Streptococcus phage phi-SsuZKB4_rum [Virus]
Lantibiotic
2664409
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A7G3MMR0/entry
RECORD: Rec_0131930 VERIFIED: NO
Provenance & Taxonomy
Streptococcus macedonicus [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A2I1YHR1/entry
RECORD: Rec_0188967 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pasteurianus [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID21633709 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21633709/; https://www.uniprot.org/uniprotkb/F5X6X4/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0196933 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pneumoniae [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
PaperGenome Sequencing Reveals a Large and Diverse Repertoire of Antimicrobial Peptides PMID30210481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30210481/
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