Peptide Database

Peptide NameCalcitonin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC148H222N38O49S2

DescriptionStandard

        CSNLSTCVLGTYSKDLNNFHTFSGIGFGAETP
    

Molecular Weight3381.70 Da

Isoelectric Point (pI)5.32

Net Charge (pH 7.0)-1.17

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.0366

GRAVY Index0.01

Hydrophobic Moment 0.46

Boman Index0.18

Instability Index-3.83

Aliphatic Index 60.94

Aromaticity 0.1250

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1397.27

LogP -18.59

H-bond Donors 50.0

H-bond Acceptors 51.0

Rotatable Bonds 106.0

Heavy Atoms 237.0

Ring Count 6.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154506 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyCalcitonin

Tax ID9615

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-7

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0182759 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyCalcitonin

Tax ID9615

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-7

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0206433 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0351437 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyCalcitonin

Tax ID9615

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-7

Bio-Activity Profile

Function

Hormone Calcium-regulatory peptide