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MYP_126858
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Basic Information
Figainin 1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C95H158N20O21
Standard
Sequence
FIGTLIPLALGALTKLFK
Physicochemical Analysis
1916.39 Da
10.00
1.76
1.55
0.0977
1.42
0.44
0.54
-14.66
162.78
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
641.73
-0.72
22.0
23.0
62.0
136.0
3.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149034 VERIFIED: YES
Provenance & Taxonomy
B. raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
NIH 3T3
13 μM
IC50
PaperPubMed PMID: 32967114 PMID32967114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32967114/
RECORD: Rec_0177543 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Human cervical carcinoma HeLa
11.1 μM
IC50
PMID32967114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32967114/
RECORD: Rec_0186689 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Candida albicans ATCC 90028
PMID32967114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32967114/
RECORD: Rec_0190048 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Antiparasitic
Staphylococcus aureus ATCC 25923
4 μM
MIC
PaperFigainin 1, a Novel Amphibian Skin Peptide with Antimicrobial and Antiproliferative Properties
RECORD: Rec_0201855 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer Antiparasitic
Klebsiella pneumoniae ATCC 13883
4 μM
MIC
PaperFigainin 1, a Novel Amphibian Skin Peptide with Antimicrobial and Antiproliferative Properties
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