Peptide Database

Peptide NameInsulin Beef

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Metabolic ▸ Glucose metabolism ▸ Antidiabetic ▸ Hypoglycemic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC255H383N65O75S6

DescriptionStandard

        GIVEQCCASVCSLYQLENYCNFVNQHLCGSHLVEALYLVCGERGFFYTPKT
    

Molecular Weight5751.55 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-2.12

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0415

GRAVY Index0.26

Hydrophobic Moment 0.44

Boman Index0.19

Instability Index5.93

Aliphatic Index 85.88

Aromaticity 0.1373

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2244.62

LogP -20.64

H-bond Donors 82.0

H-bond Acceptors 81.0

Rotatable Bonds 183.0

Heavy Atoms 401.0

Ring Count 10.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380620 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Bos taurus [Animal]

FamilyInsulin

Tax ID9606;9913

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideA6-A11, A7-B7, A20-B19

Other ModsBovine insulin sequence

Bio-Activity Profile

Function

Antidiabetic Hypoglycemic Insulin

PaperPubMed-linked source references: PMID:25941658; PMID:24673155; PMID:24118819; PMID:23448197; PMID:28250698; PMID:28295934; PMID:28282219; PMID:28275957; PMID:28234565 PMID25941658;24673155;24118819;23448197;28250698;28295934;28282219;28275957;28234565 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25941658/