Peptide Database

Peptide Name[125I][Tyr4]ghrelin (human)

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC141H235N47O42

DescriptionStandard

        GSSYLSPEHQRVQQRKESKKPPAKLQPR
    

Molecular Weight3260.66 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1731

GRAVY Index-1.82

Hydrophobic Moment 0.42

Boman Index-0.52

Instability Index73.35

Aliphatic Index 41.79

Aromaticity 0.0357

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1480.43

LogP -18.11

H-bond Donors 50.0

H-bond Acceptors 48.0

Rotatable Bonds 110.0

Heavy Atoms 230.0

Ring Count 6.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074861 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

Targetghrelin receptor (Human)

Activity0.4 nM

MethodKd