Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length135 amino acids

Chemical FormulaC678H1074N184O199S11

DescriptionStandard

        MSVMKPYLMTIAIFLILIHKASAAWNVPKCWDNMGHCRRRCLDNERYKLLCKNKVSCCIPIRKSYDDTPRPLPPLNPIQHITIDVGDWSPVSPGLNDEITFGDNEHEEISITTTEPFNSEKLKSMAPPSEKTIGN
    

Molecular Weight15339.61 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0014

GRAVY Index-0.40

Hydrophobic Moment 0.65

Boman Index-0.02

Instability Index63.43

Aliphatic Index 80.89

Aromaticity 0.0667

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6094.67

LogP -56.81

H-bond Donors 211.0

H-bond Acceptors 214.0

Rotatable Bonds 497.0

Heavy Atoms 1072.0

Ring Count 29.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329074 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Tax ID885580

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic