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MYP_126717
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Basic Information
G. mellonella moricin-like peptide C4/C5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
38 amino acids
C172H290N56O46
Standard
Sequence
KVPVGAIKKGGKAIKTGLGVVGAAGTAHEVYSHIRNRH
Physicochemical Analysis
3878.49 Da
10.66
6.02
5.65
0.1584
-0.15
0.69
0.05
14.21
92.37
0.0263
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1632.48
-17.66
58.0
55.0
131.0
274.0
5.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0199705 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
inactive: Micrococcus luteus
>150 μM
MIC
PaperThe discovery and analysis of a diverged family of novel antifungal moricin-like peptides in the wax moth Galleria mellonella
RECORD: Rec_0202942 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Escherichia coli
100 μM
MIC
PMID18207081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18207081/
RECORD: Rec_0224228 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Evidence URLhttps://patents.google.com/patent/US20100204098A1/en PatentUS 2010/0204098 A1
RECORD: Rec_0242555 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0272389 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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