Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length451 amino acids

Chemical FormulaC2171H3402N602O683S11

DescriptionStandard

        MTQILGTGEGKTSSVAKEPVVERKPAQVFFESMALAASMSGYYAGPTATTLGNSLSLGAGTAAGVGEGVAGARVLAAPNPLTVALLAIFYSPSLNEGETEMLQNIRGDQLYQNLIHSQMMVGAFTRVNSTVIQGDCVPEYELREIARQNGTVHTRVRFRIEEDPESGELVSRSYEVGEKSGLDRVRVRFAKQLNKETWGFEDPSIKGTFVWSRSAGQGKFEWGSSQTTVHDGGAGGSTTPPTPIPEPRSVWGLPNPAPASLPPVPGTPIPEEQGPNIETLPIEDRDFNDFIIVDPMGGVPAIYVYFQKASVRDLEVDYYGNFEGRSRQGLYEVDHIPSKEAVRIYLKGTYPNLKDDIIEQMTDRVAAVAIPIEVHRQCSETYGGKNNSKFRTQDGGLVTQKVLDASNLEAAVDANWDVNAECLRNEYGVSDEKIEEIRAKLHELNRKAGLY
    

Molecular Weight49216.57 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-15.91

Net Charge (pH 7.4) -16.60

Charge Density (pH 7.0) -0.0353

GRAVY Index-0.40

Hydrophobic Moment 0.64

Boman Index0.00

Instability Index41.08

Aliphatic Index 78.47

Aromaticity 0.0776

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51465.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107031 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)