Peptide Database

Peptide NameVpr 13-27

Function Ontology

Antimicrobial

Antiviral

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibition

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC88H132N18O29

DescriptionStandard

        EPYNEWTLELLEELK
    

Molecular Weight1906.09 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.15

Net Charge (pH 7.4) -4.33

Charge Density (pH 7.0) -0.2769

GRAVY Index-0.95

Hydrophobic Moment 0.40

Boman Index-0.04

Instability Index18.21

Aliphatic Index 104.00

Aromaticity 0.1333

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 773.79

LogP -2.74

H-bond Donors 25.0

H-bond Acceptors 25.0

Rotatable Bonds 62.0

Heavy Atoms 135.0

Ring Count 4.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316366 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Reverse transcriptase inhibition Integrase inhibition

MethodQualitative inhibition

RECORD: Rec_0324240 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 46.7%, E 0.0%, T 20.0%, C 33.3% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial