Peptide Database

Peptide NameiAβ5p-B1

Function Ontology

beta-sheet breaker peptides

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC25H43N5O6

DescriptionStandard

        LPALP
    

Molecular Weight509.64 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0480

GRAVY Index1.24

Hydrophobic Moment 0.29

Boman Index0.60

Instability Index123.56

Aliphatic Index 176.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 162.14

LogP 0.46

H-bond Donors 4.0

H-bond Acceptors 6.0

Rotatable Bonds 11.0

Heavy Atoms 36.0

Ring Count 2.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301404 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAmyloid-beta

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermAmidation

Other ModsαMe

Bio-Activity Profile

Function

beta-sheet breaker peptides

MethodRP-HPLC

Half-LifeRat brain homogenate, in vitro; >86400 s