Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length193 amino acids

Chemical FormulaC963H1522N264O255S9

DescriptionStandard

        PSPPPMAHEPTLLLAVTEFVANSAAFTYFTAGALRRNISSAMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLLGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRMGGTVRLTGAVPAAWTPLPVLSWAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPCPVP
    

Molecular Weight21166.59 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)8.28

Net Charge (pH 7.4) 7.94

Charge Density (pH 7.0) 0.0429

GRAVY Index0.06

Hydrophobic Moment 0.57

Boman Index0.11

Instability Index59.74

Aliphatic Index 92.02

Aromaticity 0.0777

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8092.37

LogP -96.75

H-bond Donors 278.0

H-bond Acceptors 276.0

Rotatable Bonds 654.0

Heavy Atoms 1491.0

Ring Count 47.0

Amide Bonds 207.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224622 VERIFIED: NO

Provenance & Taxonomy

OrganismAgelaius phoeniceus (Red-winged blackbird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria