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MYP_126577
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Basic Information
FluA-PB1(1-14)
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
14 amino acids
C73H120N16O19S
Standard
Sequence
MDVNPTLLFLKVPA
Physicochemical Analysis
1557.89 Da
5.59
-0.50
-0.72
-0.0357
0.82
0.22
0.34
22.61
132.14
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
550.68
-1.96
17.0
20.0
47.0
109.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007425 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
Influenza A (FluA)
0.03453±0.00219 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperIdentification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. | Wunderlich K, Mayer D, Ranadheera C, Holler AS, Mänz B, Martin A, Chase G, Tegge W, Frank R, Kessler U, Schwemmle M. | PLoS One. 2009 Oct 20;4(10):e7517. | DOI:10.1371/journal.pone.0007517 | PMID:19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0224836 VERIFIED: YES
Provenance & Taxonomy
Influenza A virus [Virus]
Virus-derived peptide
11320;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Influenza A virus (Replication); MDCK
0.03453 μM
ELISA
PaperIdentification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. | Wunderlich K, Mayer D, Ranadheera C, Holler AS, Manz B, Martin A, Chase G, Tegge W, Frank R, Kessler U, Schwemmle M. | PLoS One. 2009 | PMID:19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0232896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0235948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Influenza A(FluA):inhibition of PA-binding activity and virus replication
0.03453±0.00219 μM
IC50
PaperPubMed PMID: 19841738 PMID19841738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19841738/
RECORD: Rec_0391953 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/