Peptide Database

Peptide NameSA-hepcidin2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC80H127N25O21S8

DescriptionStandard

        CRFCCGCCTPGICGVCCRF
    

Molecular Weight2031.54 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.36

Charge Density (pH 7.0) 0.0885

GRAVY Index1.15

Hydrophobic Moment 0.33

Boman Index0.19

Instability Index22.16

Aliphatic Index 35.79

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 722.36

LogP -8.94

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 60.0

Heavy Atoms 134.0

Ring Count 3.0

Amide Bonds 18.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0373619 VERIFIED: YES

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)