Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length707 amino acids

Chemical FormulaC3315H5188N902O1035S20

DescriptionStandard

        MTRIMSTMLYIHPPHGCCAFKMEINMSDNETVPTEGVDRGHTMVVWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYHHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSNLSAGSLPETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKAEAEAKAKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEILSSLGAAVGRVIASLGATATASTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPIYVILSSPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGESPENVVMIDRLEKILKGELQPTDTDKRFYTHEVRELERYRALGIADGTVPENDYEVWNNTHTATLEDYKLSSDETLLYTPEALNSQN
    

Molecular Weight74879.38 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-29.01

Net Charge (pH 7.4) -30.25

Charge Density (pH 7.0) -0.0410

GRAVY Index-0.23

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index37.20

Aliphatic Index 79.11

Aromaticity 0.0636

Extinction Coeff. Reduced 73800.00

Extinction Coeff. Oxidized 73925.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042535 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli