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MYP_126478
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Basic Information
AMP 22
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C75H124N26O12
Standard
Sequence
LRKVWRWLRRL
Physicochemical Analysis
1581.95 Da
12.00
4.76
4.55
0.4326
-0.74
1.12
-0.52
151.75
132.73
0.1818
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
659.52
-1.33
27.0
17.0
52.0
113.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156298 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
10 μM
MIC50
PMID31954105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31954105/
RECORD: Rec_0174910 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID31954105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31954105/
RECORD: Rec_0210846 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans SC5314
2.5 μM
MIC90
PMID31954105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31954105/
RECORD: Rec_0251420 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID31954105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31954105/
RECORD: Rec_0263814 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa (80% Killing=100μM)
PMID31954105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31954105/
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