Peptide Database

Peptide NameDQ2-y-IV y-Glia (p117p132; E123 and E125)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC81H116N22O28

DescriptionStandard

        QQFSQPEQEFPQPQQ
    

Molecular Weight1845.92 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.1490

GRAVY Index-2.10

Hydrophobic Moment 0.42

Boman Index-0.32

Instability Index144.29

Aliphatic Index 0.00

Aromaticity 0.1333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 840.81

LogP -10.23

H-bond Donors 23.0

H-bond Acceptors 26.0

Rotatable Bonds 58.0

Heavy Atoms 131.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192218 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E123; Reported substitutions/positions: E125

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay

RECORD: Rec_0197668 VERIFIED: YES