Peptide Database

Peptide NameMelittin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC130H226N38O31

DescriptionStandard

        GIGAVLKVLTTGLPALIGWIKRKRQQ
    

Molecular Weight2817.42 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.1830

GRAVY Index0.29

Hydrophobic Moment 0.51

Boman Index0.13

Instability Index49.48

Aliphatic Index 135.00

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1126.32

LogP -7.85

H-bond Donors 40.0

H-bond Acceptors 36.0

Rotatable Bonds 96.0

Heavy Atoms 199.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039273 VERIFIED: YES

Provenance & Taxonomy

OrganismApis cerana [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0067774 VERIFIED: NO

Provenance & Taxonomy

OrganismApis cerana cerana [Animal]

FamilyMelittin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial