Peptide Database

Peptide NameCT1-long (C-ternimus of CsTx-1), Omega-ctenitoxin-Cs1a (45-74)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC151H256N48O38S

DescriptionStandard

        GRPMGHQAIETGLNIFRGLFKGKKKNKKTK
    

Molecular Weight3384.01 Da

Isoelectric Point (pI)11.30

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.58

Charge Density (pH 7.0) 0.2614

GRAVY Index-1.09

Hydrophobic Moment 0.66

Boman Index-0.27

Instability Index34.43

Aliphatic Index 55.33

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1440.08

LogP -14.40

H-bond Donors 50.0

H-bond Acceptors 48.0

Rotatable Bonds 123.0

Heavy Atoms 238.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169294 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetEscherichia coli SBS 363

Activity4.66-9.32 μM

MethodMIC

RECORD: Rec_0170307 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetDrosophila melanogaster

Activity82.64

MethodLD50

RECORD: Rec_0187592 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetStaphylococcus aureus ATCC 29213

Activity149 μM

MethodMIC

RECORD: Rec_0205100 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetEscherichia coli ATCC 25922

RECORD: Rec_0293537 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCyclotide

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal

TargetTrypanosoma brucei brucei MiTat1.2 221

Activity5.01 μM

MethodEC50