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MYP_126427
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Basic Information
Flt2-13
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
13 amino acids
C69H116N16O18
Standard
Sequence
SPNITVTLKKFPL
Physicochemical Analysis
1457.76 Da
10.00
1.46
1.25
0.1122
0.18
0.40
0.15
78.58
112.31
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
550.76
-3.85
18.0
20.0
45.0
103.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0103103 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
VEGFR1 / Flt-1
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
VEGF-induced angiogenesis / vascular permeability
CAM assay
PaperA small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0168832 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0169415 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 46.2%, C 53.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
RECORD: Rec_0175521 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0184413 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
VEGFR1 / Flt-1
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
VEGF-induced angiogenesis / vascular permeability
Miles vascular permeability assay
PaperA small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
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