Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC741H1165N217O219S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKATMDIGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQSLRSLLVELKVQYAGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16841.95 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0133

GRAVY Index-0.39

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index43.98

Aliphatic Index 76.16

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7044.57

LogP -72.59

H-bond Donors 248.0

H-bond Acceptors 234.0

Rotatable Bonds 563.0

Heavy Atoms 1184.0

Ring Count 26.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341073 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage KPN3 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic