Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC442H704N134O145S7

DescriptionStandard

        MRTLAILAAILLVALQAQAESLQERADEATTQEQPGEDDQDFAVSFEENGLSTLRASGSQARSTCYCRTGKCFWRESSAGWCNINGRIYRLCCR
    

Molecular Weight10439.58 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0270

GRAVY Index-0.35

Hydrophobic Moment 0.70

Boman Index-0.09

Instability Index46.68

Aliphatic Index 72.87

Aromaticity 0.0745

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4577.71

LogP -55.64

H-bond Donors 168.0

H-bond Acceptors 150.0

Rotatable Bonds 350.0

Heavy Atoms 728.0

Ring Count 10.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347644 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence