Peptide Database

Peptide NameDefensin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length104 amino acids

Chemical FormulaC522H843N151O146S9

DescriptionStandard

        MKFFVLFAILIAIVHASCASVPKVVYDGPIYELRQIEEENIEPDTELMDSNEPLLPLRHRRVTCDVLSWQSKWLSINHSACAIRCLAQRRKGGSCRNGVCICRK
    

Molecular Weight11858.79 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)2.71

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0261

GRAVY Index0.00

Hydrophobic Moment 0.56

Boman Index0.00

Instability Index76.16

Aliphatic Index 100.29

Aromaticity 0.0673

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4776.18

LogP -42.40

H-bond Donors 174.0

H-bond Acceptors 161.0

Rotatable Bonds 393.0

Heavy Atoms 828.0

Ring Count 17.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104009 VERIFIED: NO

Provenance & Taxonomy

OrganismApis mellifera [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence