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MYP_126331
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Basic Information
[D-Trp]CJ-15,208
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
4 amino acids
C34H37N5O5
Standard
Sequence
FPFW
Physicochemical Analysis
595.69 Da
5.53
-0.24
-0.44
-0.0600
0.78
0.27
0.83
103.80
0.00
0.7500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
157.62
2.57
5.0
5.0
12.0
44.0
5.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0170079 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lactam
Lactam
p=D-Proline; w=D-Tryptophane
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
16.5±0.7 μM
IC50
PaperPubMed PMID: 28692379 PMID28692379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28692379/
RECORD: Rec_0228898 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lactam
Lactam
p=D-Proline; w=D-Tryptophane
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28692379 PMID28692379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28692379/
RECORD: Rec_0283489 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lactam
p=D-Proline
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28692379 PMID28692379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28692379/
RECORD: Rec_0334363 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lactam
p=D-Proline
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28692379 PMID28692379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28692379/
RECORD: Rec_0377091 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lactam
p=D-Proline
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
10.1±0.9 μM
IC50
PaperPubMed PMID: 28692379 PMID28692379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28692379/
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