MYP_126315
Basic Information
IPB06(SARS-CoV-2-S (1183-1205))
Antimicrobial
Antiviral
Antiviral Anti-Coronavirus Anti-SARS-CoV
Antiviral Anti-Coronavirus Anti-SARS-CoV-2
Antiviral Antiviral mechanism Viral fusion inhibition
Membrane / Ion-channel modulation Sodium channel modulation Sodium channel inhibitor
Standard
23 amino acids
C113H194N32O39
Standard
Sequence
IDRLNEVAKNLNESLIDLQELGK
Physicochemical Analysis
2624.94 Da
4.51
-2.23
-2.44
-0.0970
-0.48
0.69
-0.12
33.52
135.65
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1196.55
-11.36
39.0
37.0
95.0
184.0
0.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0394703 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Chol
Bio-Activity Profile
Antimicrobial Anti-SARS-CoV-2
SARS-CoV-2:inhibition of cell-cell fusion in 293T/ACE2 cells
5 μM
IC50
RECORD: Rec_0413667 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome coronavirus 2 [Virus]
HR2-derived fusion inhibitor
2697049
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Lys side-chain cholesterol conjugation
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus 2
1.037 μM
IC50
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