Peptide Database

Peptide NameColicin-E2 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC482H767N157O143S2

DescriptionStandard

        MRDQKFNNFDEFRRKLWEEVSKDPELSKNFIQSNRTRMRNGLSPRARYKDSVGGRRSFELHHDKQISQGGEVYDIDNIRVATPKRHIDIHKGK
    

Molecular Weight11113.34 Da

Isoelectric Point (pI)10.06

Net Charge (pH 7.0)6.86

Net Charge (pH 7.4) 6.41

Charge Density (pH 7.0) 0.0738

GRAVY Index-1.32

Hydrophobic Moment 0.60

Boman Index-0.39

Instability Index63.46

Aliphatic Index 56.56

Aromaticity 0.0860

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4997.27

LogP -55.04

H-bond Donors 176.0

H-bond Acceptors 156.0

Rotatable Bonds 387.0

Heavy Atoms 784.0

Ring Count 16.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336539 VERIFIED: NO

Provenance & Taxonomy

OrganismProteus mirabilis [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal