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MYP_126281
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Basic Information
Angiotensin-2
Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Reproductive biology ▸ Reproductive modulation
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
8 amino acids
C50H71N13O12
Standard
Sequence
DRVYIHPF
Physicochemical Analysis
1046.18 Da
6.74
-0.15
-0.41
-0.0191
-0.33
0.39
0.03
25.80
85.00
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
406.34
-1.10
14.0
13.0
29.0
75.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0354063 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Vasopressor Cardiovascular
Angiotensin II receptor
Clinical/Human: Plasma half-life < 1 min
Evidence URLhttps://www.accessdata.fda.gov/drugsatfda_docs/label/2017/209360s000lbl.pdf
RECORD: Rec_0388702 VERIFIED: YES
Provenance & Taxonomy
Gorilla gorilla gorilla [Animal]
Serpin
9595
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID22707160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22707160/
RECORD: Rec_0391055 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin peptide
9606
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Host-response modulator Anti-SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
PMID36584778 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/36584778/
RECORD: Rec_0413728 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Serpin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID22707160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22707160/
RECORD: Rec_0426622 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Angiotensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
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