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MYP_126281
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Basic Information
Angiotensin-2
Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Reproductive biology ▸ Reproductive modulation
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
8 amino acids
C50H71N13O12
Standard
Sequence
DRVYIHPF
Physicochemical Analysis
1046.18 Da
6.74
-0.15
-0.41
-0.0191
-0.33
0.39
0.03
25.80
85.00
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
406.34
-1.10
14.0
13.0
29.0
75.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272840 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Serpin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Beta-decarboxylated aspartate, in form angiotensin-A
Bio-Activity Profile
Secreted protein
PMID22707160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22707160/
RECORD: Rec_0284614 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Serpin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID3081342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3081342/
RECORD: Rec_0322987 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Serpin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID3081342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3081342/
RECORD: Rec_0331774 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
1:Beta-decarboxylated aspartate
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation Receptor modulation
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
RECORD: Rec_0336955 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Angiotensin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Angiotensin-2 (Ovis aries): PMID 3081342 PMID3081342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3081342/
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