‹ ›
MYP_126271
← PREVIOUS NEXT → BACK
Basic Information
Crotamine
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
42 amino acids
C214H332N64O54S7
Standard
Sequence
YKQCHKKGGHCFPKEKICLPPSSDFGKMDCRWRWKCCKKGSG
Physicochemical Analysis
4889.78 Da
9.51
7.87
7.46
0.1874
-1.10
0.46
-0.27
82.60
18.57
0.1190
12490.00
12865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1912.88
-18.07
73.0
71.0
164.0
339.0
12.0
42.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0031785 VERIFIED: NO
Provenance & Taxonomy
Animalia [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0034082 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Antifungal Hemolytic
PaperPubMed PMID: 19706485 | PubMed PMID: 16185738 | PubMed PMID: 1176086 | PubMed PMID: 9839677 | PubMed PMID: 22142367 | PubMed PMID: 210622 PMID19706485;16185738;1176086;9839677;22142367;210622 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19706485/
RECORD: Rec_0050507 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Antiparasitic Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0113118 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Antifungal
Staphylococcus aureus
PaperPubMed PMID: 19706485 | PubMed PMID: 16185738 | PubMed PMID: 1176086 | PubMed PMID: 9839677 | PubMed PMID: 22142367 | PubMed PMID: 210622 PMID19706485;16185738;1176086;9839677;22142367;210622 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19706485/
RECORD: Rec_0117836 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Crotamine
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Breast cancer (cell line not reported)
PaperCancerPPD2 curated year-page record; primary PMID 10531277 (1999), additional curated PMID 18957441. PMID10531277;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4