Peptide Database

Peptide NameVarv E

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC114H182N34O39S5

DescriptionStandard

        GLPIGETCVGGTCNTPGCSCSWPVCTRN
    

Molecular Weight2813.19 Da

Isoelectric Point (pI)5.97

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.56

Charge Density (pH 7.0) -0.0102

GRAVY Index0.07

Hydrophobic Moment 0.26

Boman Index0.15

Instability Index41.02

Aliphatic Index 48.57

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1145.20

LogP -17.67

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 82.0

Heavy Atoms 192.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010254 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetHaemonchus contortus

Activity0.9

MethodIC50

RECORD: Rec_0367181 VERIFIED: YES