Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC412H646N114O118S14

DescriptionStandard

        MKTFSVAVAVAVVLTFICLQESSAVSFTEVQELEEPMSNDGPIAAYKEMPEDSWKMGYGSRRWKCRFCCRCCPRMRGCGLCCRF
    

Molecular Weight9533.14 Da

Isoelectric Point (pI)8.10

Net Charge (pH 7.0)1.43

Net Charge (pH 7.4) 1.06

Charge Density (pH 7.0) 0.0170

GRAVY Index0.01

Hydrophobic Moment 0.65

Boman Index0.01

Instability Index70.13

Aliphatic Index 59.17

Aromaticity 0.1071

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3720.15

LogP -35.64

H-bond Donors 141.0

H-bond Acceptors 134.0

Rotatable Bonds 311.0

Heavy Atoms 658.0

Ring Count 15.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038465 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal